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Tumor-educated Gr1 <sup>+</sup> CD11b <sup>+</sup> cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6–JAK signaling

2022-10-27

Abstract excerpt

Cancer cell plasticity contributes to tumor therapy resistance and metastasis formation, which represent the main causes of cancer-related death for most cancers, including breast cancer. The tumor microenvironment drives cancer cell plasticity and metastasis and, thus, unravelling the underlying cues may provide novel effective strategies to manage metastatic disease. Here, we show that stem cell antigen-1 positi...

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Literature Corpus work
ae9c340e-b5b8-5d7b-b0f1-aeb6b281f699
DOI
10.1101/2022.10.26.513889
Open publication

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Tumor-educated Gr1 <sup>+</sup> CD11b <sup>+</sup> cells instigate breast cancer metastasis by twisting cancer cells plasticity via OSM/IL6–JAK signalingDOI 10.1101/2022.10.26.513889
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