Article

Engineering mRNA-LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative diseases

2025-10-09

Abstract excerpt

Messenger-RNA (mRNA) therapeutics delivered by lipid nanoparticles (LNPs) have advanced from concept to clinic at unprecedented speed, yet their promise for neurodegenerative diseases remains largely untapped. Currently intractable age-related proteinopathies such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis demand new therapies that combine molecular precision with scalable manuf...

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Literature Corpus work: ae482ab6-bd92-5278-858f-5d39a7a4d154
DOI: 10.22541/au.176004563.31962211/v1

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