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mRNA Vaccines Five Years After COVID-19: Lessons in Platform Design, Real-World Effectiveness, and Equity

2026-07-06

Abstract excerpt

The COVID-19 pandemic elevated messenger RNA (mRNA) technology from an obscure concept to a proven vaccine platform, largely due to the nucleoside-modification discovery by Karikó and Weissman, which earned them the 2023 Nobel Prize. Five years post-initial authorizations, this review examines the platform's evolution across three key areas. Firstly, platform design has expanded significantly beyond the initial li...

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Literature Corpus work
15d075b1-e9db-58d1-9e78-91e5eb4fd3c3
DOI
10.20944/preprints202607.0288.v1
Open publication

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