Article

<i>Ex vivo</i> mass cytometry analysis reveals a profound myeloid proinflammatory signature in psoriatic arthritis synovial fluid

2021-03-04

Abstract excerpt

<h4>Objectives</h4> A number of immune populations have been implicated in psoriatic arthritis (PsA) pathogenesis. This study used mass cytometry (CyTOF) combined with transcriptomic analysis to generate a high-dimensional dataset of matched PsA synovial fluid (SF) and blood leucocytes, with the aim of identifying cytokine production ex vivo in unstimulated lymphoid and myeloid cells. <h4>Methods</h4> Fresh SF...

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Literature Corpus work: ae333c34-39f6-5c9b-a2f4-a88050d95fc0
DOI: 10.1101/2021.03.04.433903

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