Article

Costing ‘the’ MTD … in 2-D

2018-07-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> I have previously evaluated the efficiency of one-size-fits-all dosing for single agents in oncology (Norris 2017b). By means of a generic argument based on an E max -type dose-response model, I showed that one-size-fits-all dosing may roughly halve a drug’s value to society. Since much of the past decade’s ‘innovation’ in oncology dose-finding methodology has involved the...

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Literature Corpus work: ae1d82de-c1be-525a-b947-212ee8abbdca
DOI: 10.1101/370817

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