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The influence of host genetics and different >Mycobacterium tuberculosis strains on macrophage functions and clinical outcome of tuberculosis disease

2017-01-01

Abstract excerpt

Only 5-10 % of <i>Mycobacterium tuberculosis (Mtb)</i> infected individuals develop active pulmonary TB (PTB), and around < 1 % develop disseminated TB meningitis (TBM). Macrophages are one of the first defense barriers, but it is unclear how their antimicrobial activities influence TB presentations and clinical outcomes. Many studies have shown host and bacterial genetics are important factors in TB susceptibilit...

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Literature Corpus work
adfe3a20-ea02-5f5d-b463-4cb8f6792d1b
DOI
10.21954/ou.ro.0000ce44
Open publication

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