Article

Statistical model integrating interactions into genotype-phenotype association mapping: an application to reveal 3D-genetic basis underlying Autism

2020-07-27

Abstract excerpt

Biological interactions are prevalent in the functioning organisms. Correspondingly, statistical geneticists developed various models to identify genetic interactions through genotype-phenotype association mapping. The current standard protocols in practice test single variants or single regions (that contain multiple local variants) sequentially along the genome, followed by functional annotations that involve va...

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Literature Corpus work: adec02bc-d098-5e9f-98a8-ad5c37310013
DOI: 10.1101/2020.07.27.222364

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