Article

Electrophysiological and molecular characterization of a TGF-β1 goat model

2026-07-08

Abstract excerpt

<title>Abstract</title> <p>Atrial Fibrillation (AF) is the most common cardiac arrhythmia in adult humans. Atrial fibrosis plays a primary role in developing and sustaining this disease phenotype. Specifically, TGF-β1, a potent pro-fibrotic molecule, is implicated in cell turnover, increasing the amount of extracellular matrix in the heart. This increase leads to aberrant electrical signaling and can produce AF....

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Literature Corpus work: ad483788-b03e-5e3c-8ab2-367bd081fca8
DOI: 10.21203/rs.3.rs-10232704/v1

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