Article

Multi-omics Analysis Reveals the Anti-tumor Efficacy of Calycosin in Nasopharyngeal Carcinoma and its Mechanism of Overcoming ABCC1-Mediated Resistance

2026-08-25

Abstract excerpt

<title>Abstract</title> <p>This study aimed to elucidate the antitumor effects and drug-resistance mechanisms of calycosin (CA) in nasopharyngeal carcinoma (NPC) and identify potential combination strategies targeting adaptive resistance pathways. In vitro C666-1 NPC cell models and subcutaneous xenograft models in nude mice were used to evaluate CA efficacy. Network pharmacology, GEO transcriptomic cohorts, RNA...

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Literature Corpus work: ad0de9b0-381b-591d-8ac5-a663f09bd148
DOI: 10.21203/rs.3.rs-10654494/v1

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