Article
Network-based analysis with primary cells reveals drug response landscape of acute myeloid leukemia.
Experimental cell research - 1 Aug 2020
Chen Cheng, Wang Li, Li Lili, Wang Aoli, Huang Tao, Hu Jie, Zhao Ming, Liu Feiyang, Qi Shuang, Hu Chen, Wang Wenliang, Liu Jing, Ge Jian, Xia Ruixiang, Wang Wenchao, Liu Qingsong
Abstract excerpt
Acute myeloid leukemia (AML) is one of the most common, complex, and heterogeneous hematological malignancies in adults. Despite progresses in understanding the pathology of AML, the 5-year survival rates still remain low compared with CML, CLL, etc. The relationship between genomic features and drug responses is critical for precision medication. Herein, we depicted a picture for response of 145 drugs against 33...
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