Article
Targeting annexin A2 reduces tumorigenesis and therapeutic resistance of nasopharyngeal carcinoma.
Oncotarget - 29 Sept 2015
Chen Chang-Yu, Lin Yung-Song, Chen Chi-Long, Chao Pin-Zhir, Chiou Jeng-Fong, Kuo Chia-Chun, Lee Fei-Peng, Lin Yung-Feng, Sung Yu-Hsuan, Lin Yun-Tien, Li Chang-Fan, Chen Yin-Ju, Chen Chien-Ho
Abstract excerpt
The expression of annexin A2 (ANXA2) in nasopharyngeal carcinoma (NPC) cells induces the immunosuppressive response in dendritic cells; however, the oncogenic effect and clinical significance of ANXA2 have not been fully investigated in NPC cells. Immunohistochemical staining for ANXA2 was performed in 61 patients and the association with clinicopathological status was determined. Short hairpin (sh)RNA knockdown...
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