Article
Parainflammation, chronic inflammation, and age-related macular degeneration.
Journal of leukocyte biology - 1 Nov 2015
Chen Mei, Xu Heping
Abstract excerpt
Inflammation is an adaptive response of the immune system to noxious insults to maintain homeostasis and restore functionality. The retina is considered an immune-privileged tissue as a result of its unique anatomic and physiologic properties. During aging, the retina suffers from a low-grade chronic oxidative insult, which sustains for decades and increases in level with advancing age. As a result, the retinal...
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