Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans.

PLoS biology - 1 Sept 2013

Ni Min, Feretzaki Marianna, Li Wenjun, Floyd-Averette Anna, Mieczkowski Piotr, Dietrich Fred S, Heitman Joseph

Abstract excerpt

Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer and genetic disorders such as trisomy 21 in Down's syndrome. In contrast, aneuploidy can also be advantageous and in fungi confers antifungal drug resistance and enables rapid adaptive evolution. We report here that sexual reproduction generates phenotypic and genotypic diversity in the human pathogenic yeast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Antifungal Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cryptococcosis

Share to Cryptococcus neoformans

Share to Drug Resistance, Fungal

Share to Fluconazole

Share to Genes, Mating Type, Fungal

Share to Reproduction, Asexual

Source

Open in PubMed Open full text

Identifiers

PMID: 24058295
DOI: 10.1371/journal.pbio.1001653
PMCID: PMC3769227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unisexual and heterosexual meiotic reproduction generate aneuploidy and phenotypic diversity de novo in the yeast Cryptococcus neoformans.PMID 24058295Read ↗

Unisexual reproduction drives meiotic recombination and phenotypic and karyotypic plasticity in Cryptococcus neoformans.Semantic proximity Read ↗

Unisexual reproduction reverses Muller's ratchet.Semantic proximity Read ↗

Diploids in the Cryptococcus neoformans serotype A population homozygous for the alpha mating type originate via unisexual mating.Semantic proximity Read ↗

Unisexual reproduction in the global human fungal pathogen <i>Cryptococcus neoformans</i>Semantic proximity Read ↗

Unisexual reproduction in the global human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

A High-Resolution Map of Meiotic Recombination in Cryptococcus deneoformans Demonstrates Decreased Recombination in Unisexual ReproductionSemantic proximity Read ↗

A High Resolution Map of Meiotic Recombination in <i>Cryptococcus</i> Demonstrates Decreased Recombination in Unisexual ReproductionSemantic proximity Read ↗

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformansSemantic proximity Read ↗

Mechanisms of unisexual mating in Cryptococcus neoformans.Semantic proximity Read ↗

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen <i>Cryptococcus deneoformans</i>Semantic proximity Read ↗

Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and alpha isolates.Semantic proximity Read ↗

Unisexual reproduction enhances fungal competitiveness by promoting habitat exploration via hyphal growth and sporulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.