Article

Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

2024-10-24

Abstract excerpt

<h4>Background: </h4> Bulk transcriptomic analyses of high-grade serous ovarian cancer (HGSOC) so far have not uncovered potential drug targets, possibly because subtle, disease-relevant transcriptional patterns are overshadowed by dominant, non-relevant ones. Our aim was to uncover disease-outcome-related patterns in HGSOC transcriptomes that may reveal novel drug targets. <h4>Method:</h4> Using consensus-indepen...

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Literature Corpus work: accdfb56-89f3-50e3-8bb3-1a2323b1daff
DOI: 10.1101/2024.10.21.619015

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