Article

Hidden in plain sight: What remains to be discovered in the eukaryotic proteome?

2018-11-16

Abstract excerpt

The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to funda...

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Literature Corpus work: ac91c770-5f2d-5e72-90ef-51b4f5ea20f5
DOI: 10.1101/469569

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