Article

Analysis of Arabidopsis <i>venosa4-0</i> supports the role of VENOSA4 in dNTP homeostasis

2023-04-01

Abstract excerpt

<h4>ABSTRACT</h4> An imbalance in the deoxyribonucleoside triphosphate (dNTP) pool caused by an increase or decrease in the levels of any of the four dNTPs leads to increased DNA mutations, overloading DNA repair mechanisms. The human protein SAMHD1 (Sterile alpha motif and histidine-aspartate domain containing protein 1) functions as a dNTPase to maintain the balance of the dNTP pool, as well as in DNA repair. I...

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Literature Corpus work: ac55e692-5170-5f97-9a02-c96d8b76431d
DOI: 10.1101/2023.03.30.534755

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