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Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer’s Disease and Associated Amyloid-Disease Brain Tissue

2023-05-12

Abstract excerpt

<h4>ABSTRACT</h4> Antibodies that target the β-amyloid peptide (Aβ) and its associated assemblies are important tools in Alzheimer’s disease research and have emerged as promising Alzheimer’s disease therapies. This paper reports the creation and characterization of a triangular Aβ trimer mimic composed of Aβ l7-36 β-hairpins, and the generation and study of polyclonal antibodies raised against the Aβ trimer mim...

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Literature Corpus work
ac547f54-a9bb-5526-b7a6-b7023ecd3f43
DOI
10.1101/2023.05.11.540404
Open publication

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Antibodies Raised Against an Aβ Oligomer Mimic Recognize Pathological Features in Alzheimer’s Disease and Associated Amyloid-Disease Brain TissueDOI 10.1101/2023.05.11.540404
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