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Genetic study of intrahepatic cholestasis of pregnancy in 101,023 Chinese women unveils East Asian-specific etiology linked to historic HBV infection

2024-07-03

Abstract excerpt

<h4>Background & Aims</h4> Intrahepatic cholestasis of pregnancy (ICP) is the most common and high-risk liver disorder during the critical period of human reproduction. Despite varying prevalence across populations, a mechanistic understanding of this phenomenon is lacking. This study delves into the genetic etiology of ICP in East Asians, drawing comparisons with Europeans to comprehend ICP etiology in the contex...

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Literature Corpus work
ac4c48d0-d12d-5f4c-9029-af38992363a5
DOI
10.1101/2024.07.01.24309754
Open publication

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Genetic study of intrahepatic cholestasis of pregnancy in 101,023 Chinese women unveils East Asian-specific etiology linked to historic HBV infectionDOI 10.1101/2024.07.01.24309754
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