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Screening of Hematopoietic Small Molecules Facilitates the Establishment of a Chemically Defined Hsc Expansion Medium With Enhanced Performance

2021-03-02

Abstract excerpt

<title>Abstract</title> <p>Hematopoietic stem cells (HSC), known for their ability to multipotent and self-renew, are often used in HSC transplantation for the treatment of hematological diseases and malignancies. Umbilical cord blood (UCB) and mobilized peripheral blood (mPB), which are alternatives to bone marrow (BM) for HSC transplantation, have reduced HSC. To address this restriction, the ex vivo expansion...

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Literature Corpus work
ac317d6d-c94b-5e02-8a14-d3f791fe6294
DOI
10.21203/rs.3.rs-254465/v1
Open publication

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Screening of Hematopoietic Small Molecules Facilitates the Establishment of a Chemically Defined Hsc Expansion Medium With Enhanced PerformanceDOI 10.21203/rs.3.rs-254465/v1
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