Article

The Hippo effector TAZ cooperates with oncogenic β-catenin in experimental and human hepatoblastoma development

2019-12-06

Abstract excerpt

<title>Abstract</title> <p>Backgrounds: Hepatoblastoma (HB) is the most common pediatric liver tumor. Though Wnt/β-catenin and Hippo cascades are implicated in HB development, there is no study on the crosstalk of β-catenin and Hippo downstream effector TAZ in HB. <h4>Methods:</h4> The expression of TAZ and of β-catenin in human HB specimens was assessed by immunohistochemistry (IHC). The functional interplay bet...

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Literature Corpus work: ac27e5f5-8119-5146-ad96-246aa5fcc229
DOI: 10.21203/rs.2.18319/v1

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