Article

Liver Kinome Profiling Identifies PS1145 as a Potential Therapeutic molecule for amelioration of Systemic Inflammation in Alcohol-related Liver Disease

2025-07-05

Abstract excerpt

<h4>Background and aims</h4> Alcohol-related liver disease (ALD) has high mortality due to systemic inflammation. We analysed liver and monocyte kinome profiles in a chronic ethanol-fed pre-clinical rat model to identify therapeutic targets that could mitigate inflammation in ALD. <h4>Method</h4> Kinome profile was performed in liver and circulating monocytes at baseline, and after 8,12,16,20 and 24-weeks of 40%...

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Literature Corpus work: 44070240-d5e8-583c-8ae0-4614736bbe66
DOI: 10.1101/2025.07.02.662754

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Liver Kinome Profiling Identifies PS1145 as a Potential Therapeutic molecule for amelioration of Systemic Inflammation in Alcohol-related Liver DiseaseDOI 10.1101/2025.07.02.662754Read

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