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Alcoholic fatty liver disease inhibited the co-expression of Fmo5 and PPARα to activate the NF-κB signaling pathway, thereby reducing liver injury via inducing gut microbiota disturbance 

2020-11-04

Abstract excerpt

<h4>Background: </h4> Alcohol-induced intestinal dysbiosis disrupts and inflammatory responses are essential in the development of alcoholic fatty liver disease (AFLD). Here, we investigated the effects of Fmo5 on changes in enteric microbiome composition in a model of AFLD and dissected the pathogenic role of Fmo5 in AFLD-induced liver pathology. <h4>Methods: </h4> The expression profile data of GSE8006 and GSE40...

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Literature Corpus work
a2f50194-e7a0-59da-a3e9-c7f04e88a28a
DOI
10.21203/rs.3.rs-40866/v2
Open publication

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Alcoholic fatty liver disease inhibited the co-expression of Fmo5 and PPARα to activate the NF-κB signaling pathway, thereby reducing liver injury via inducing gut microbiota disturbance&nbsp;DOI 10.21203/rs.3.rs-40866/v2
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