Article

Understanding the effects of oxytocin receptor variants on OXT–OXT receptor binding: A mathematical model

2024-10-17

Abstract excerpt

<title>Abstract</title> <p>Approximately half of U.S. women giving birth annually receive Pitocin, the synthetic form of oxytocin (OXT), yet its effective dose can vary significantly. To address the need for improved dosing, we developed a data-driven mathematical model to predict OXT receptor (OXTR) binding. Our study focuses on five prevalent OXTR variants (V45L, P108A, L206V, V281M, and E339K) and their impact...

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Literature Corpus work: ac1c4cdf-25f8-5315-9c15-836426835fd9
DOI: 10.21203/rs.3.rs-5251740/v1

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