Article
Influence of oxytocin receptor single nucleotide sequence variants on contractility of human myometrium: an in vitro functional study.
BMC medical genetics - 12 Nov 2019
Füeg F, Santos S, Haslinger C, Stoiber B, Schäffer L, Grünblatt E, Zimmermann R, Simões-Wüst A P
Abstract excerpt
BACKGROUND: Oxytocin receptor (OXTR) gene variants have been shown to affect the prevalence of preterm birth, mode of delivery and oxytocin (OXT) requirements for labor induction and augmentation. We hypothesized that this might be associated with different myometrium responses to oxytocin. Our aim was to investigate the influence of a selection of eight OXTR gene single nucleotide variants on oxytocin-induced...
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