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Brain penetrant calcium channel blockers do not reduce alcohol consumption: Converging results from two large independent cohort studies using electronic health records

2026-03-02

Abstract excerpt

Alcohol use disorder (AUD) remains a major public health problem, with few effective medications and suboptimal adherence. L-type calcium channel blockers (LTCCBs) have genetic and preclinical support as potential treatments for AUD. We evaluated whether brain penetrant (BP)-LTCCBs are associated with reduced alcohol consumption by conducting two preregistered ( https://osf.io/huawv ) observational cohort studies...

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Literature Corpus work
ac1541a2-3084-573d-b69b-f24ea9ef1425
DOI
10.64898/2026.02.23.26346644
Open publication

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Brain penetrant calcium channel blockers do not reduce alcohol consumption: Converging results from two large independent cohort studies using electronic health recordsDOI 10.64898/2026.02.23.26346644
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