Article
Balancing risk and benefit in heavy drinkers treated with topiramate: implications for personalized care.
The Journal of clinical psychiatry - 1 Mar 2016
Feinn Richard, Curtis Brenda, Kranzler Henry R
Abstract excerpt
BACKGROUND: Despite topiramate's ability to reduce heavy drinking, its adverse effects may limit its clinical utility. METHOD: To evaluate the risks and benefits of topiramate, we reanalyzed data from a completed trial of the medication in 138 heavy drinkers whose goal was to reduce their drinking to safe levels. We used the number of patients who had no heavy drinking days during the last 4 weeks of treatment to...
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