Article

A machine learning approach to predict drug-induced autoimmunity using transcriptional data

2023-04-04

Abstract excerpt

Drug-induced autoimmunity (DIA) is an idiosyncratic adverse drug reaction. Although first reported in the mid-1940’s, the mechanisms underlying DIA remain unclear, and there is little understanding of why it is only associated with some drugs. Because it only occurs in a small number of patients, DIA is not normally detected until a drug has reached the market. We describe an ensemble machine learning approach usi...

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Literature Corpus work: abc9cf30-7d24-5271-8009-8b1e87c8372c
DOI: 10.1101/2023.04.04.533417

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