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<i>Scribble</i> knockdown induced metastasis tracking, identification of its associated novel molecular candidates through Proteome and <i>in silico</i> studies

2024-04-13

Abstract excerpt

Metastasis is the primary cause of cancer associated death globally. Loss of function of Scribble , a cell polarity regulator/tumor suppressor gene, is associated with many forms of human cancer but its role in cell proliferation and metastasis remains unknown. We generated metastatic cancer in Drosophila using UAS-GAL4 system, through knockdown of Scribble in the wing imaginal discs and tracked metastasis even...

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Identifiers and source

Literature Corpus work
87c944a4-110c-5de2-9498-7233393d9e8b
DOI
10.1101/2024.04.09.588727
Open publication

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