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Article

Drp1-mediated mitochondrial fission regulates calcium and F-actin dynamics during wound healing.

Biology open - 3 May 2020

Ponte Susana, Carvalho Lara, Gagliardi Maria, Campos Isabel, Oliveira Paulo J, Jacinto António

Abstract excerpt

Mitochondria adapt to cellular needs by changes in morphology through fusion and fission events, referred to as mitochondrial dynamics. Mitochondrial function and morphology are intimately connected and the dysregulation of mitochondrial dynamics is linked to several human diseases. In this work, we investigated the role of mitochondrial dynamics in wound healing in the Drosophila embryonic epidermis. Mutants for...

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PMID: 32184231
DOI: 10.1242/bio.048629
PMCID: PMC7225088

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