Article

An Integrated Preclinical Platform for Lethal Neuroendocrine Prostate Cancer from Rapid Autopsy Bone and Liver Metastases

2026-07-23

Abstract excerpt

<h4>SUMMARY</h4> Treatment-emergent neuroendocrine prostate cancer (NEPC) is an aggressive, therapy-resistant disease arising in up to 20% of castration resistant prostate cancers, yet robust biologically relevant preclinical models remain scarce. Here, we describe a technical blueprint for establishing an integrated platform of patient-derived models from visceral and bone metastases collected through a prostate...

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Literature Corpus work: ab14a583-083d-5d6d-98a2-6d2b7c6a0a04
DOI: 10.64898/2026.07.22.740121

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