Article

Fyn interrupts telomere maintenance in stem cells by phosphorylating menin at tyrosine 603

2022-04-01

Abstract excerpt

<title>Abstract</title> <p>Telomeres protect chromosome ends and determine the proliferative potential of cells. The canonical telomere sequence TTAGGG is synthesized by telomerase holoenzyme, which maintains telomere length in proliferative stem cells. Although the core components of telomerase are well defined, many aspects of telomerase regulation are poorly understood. We report a novel role for the Src famil...

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Literature Corpus work: ab0fc5c3-ad69-5546-a56d-a1526027f136
DOI: 10.21203/rs.3.rs-1425640/v1

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