Article

Somatic evolution of metabolic reprograming: mutation limited or selection limited?

2026-08-04

Abstract excerpt

Somatic mutations can potentially be responsible for metabolic reprogramming, but the crucial question is whether the evolution would be mutation limited or selection limited. Mathematical and statistical considerations make the case for selection limited evolution stronger, e.g. somatic evolution of cancer is shown to be selection limited than mutation limited. Although some insights are developing into the selec...

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Literature Corpus work: aa875b9d-a0a8-5867-ac5b-f0f19de5c586
DOI: 10.32942/x28686

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