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Article

A global profile of glucose-sensitive endothelial-expressed long non-coding RNAs

19 Jul 2016

Abstract excerpt

Hyperglycemia-related endothelial dysfunction is believed to be the crux of diabetes-associated micro- and macro-vascular complications. We conducted a systematic transcriptional survey to screen for human endothelial long non-coding RNAs (lncRNAs) regulated by elevated glucose levels. lncRNAs and protein-coding transcripts from human umbilical vein endothelial cells (HUVECs) cultured under high (25 mmol/L) or...

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PMID: 27434139
DOI: 10.1139/cjpp-2015-0585

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