Article

Loss of Tbx3 in mouse eye causes retinal angiogenesis defects reminiscent of human disease

2022-04-22

Abstract excerpt

<h4>Purpose</h4> In Retinopathy of Prematurity (ROP), infants often have incomplete vascularization, affecting the temporal region. A factor expressed in this region during retinal development is the T-box factor, Tbx3 , which has not been studied in the mammalian eye. The purpose of this study was to determine if Tbx3 is required during eye formation for retinal angiogenesis. <h4>Methods</h4> Conditional rem...

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Literature Corpus work: aa46c201-dfac-5489-9d77-ae75203582d8
DOI: 10.1101/2022.04.20.488944

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