Article
Geography is a better determinant of human genetic differentiation than ethnicity.
Human genetics - 1 Dec 2005
Manica Andrea, Prugnolle Franck, Balloux François
Abstract excerpt
Individuals differ genetically in their susceptibility to particular diseases and their response to drugs. However, personalized treatments are difficult to develop, because disease susceptibility and drug response generally have poorly characterized genetic architecture. It is thus tempting to use the ethnicity of patients to capture some of the variation in allele frequencies at the genes underlying a clinical...
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