Article
Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations.
PloS one - 1 Jan 2017
Reisberg Sulev, Iljasenko Tatjana, Läll Kristi, Fischer Krista, Vilo Jaak
Abstract excerpt
Polygenic risk scores are gaining more and more attention for estimating genetic risks for liabilities, especially for noncommunicable diseases. They are now calculated using thousands of DNA markers. In this paper, we compare the score distributions of two previously published very large risk score models within different populations. We show that the risk score model together with its risk stratification...
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