Article
Network Pharmacology and Molecular Docking Uncover Novel Candidate Compound-Target Actions of Yokukansan (Yi-Gan San) in the Behavioral and Psychological Symptoms of Dementia
2026-07-21
Abstract excerpt
<h4>Background: </h4> Yokukansan (YKS; Yi-Gan San, TJ-54), a 7-herb Kampo formula, is widely prescribed to ameliorate the behavioral and psychological symptoms of dementia (BPSD), including those arising in Alzheimer's disease (AD). Although YKS improves the behavioral and psychological symptoms of dementia in randomized trials, a compound-resolved map of which YKS constituents act on which BPSD-relevant proteins...
Topics
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- Alzheimer's disease research and treatments
- Bioinformatics and Genomic Networks
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Ginseng Biological Effects and Applications
- Medicinal Plants and Bioactive Compounds
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- 885a7374-ebfd-53ed-9216-53f3ed9e705f
- DOI
- 10.20944/preprints202607.1493.v1
