Article

<i>In vivo</i> molecular signatures of cerebellar pathology in spinocerebellar ataxia type 3

2020-01-07

Abstract excerpt

<h4>Background</h4> No treatment exists for the most common dominantly inherited ataxia Machado-Joseph disease, or spinocerebellar ataxia type 3 (SCA3). Successful evaluation of candidate therapeutics will be facilitated by validated noninvasive biomarkers of aspects of disease pathology recapitulated by animal models. <h4>Objective</h4> We sought to identify shared neurochemical signatures in two mouse models o...

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Literature Corpus work: a99d4dae-8130-5a84-879e-4800e0ac5d18
DOI: 10.1101/2020.01.03.894337

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