Article

Back to basics: Immunoglobulin germline reference sequences enable investigations and reveal insights into bat-specific immunity

2025-04-16

Abstract excerpt

<h4>Summary</h4> We generated a highly-contiguous, annotated genome of the Jamaican fruit bat, Artibeus jamaicensis, including annotated germline immunoglobulin heavy chain (IGH) and light chain (IGL) loci to understand bat B cell receptor repertoires. The bat germline shares many structures and features described in human immunoglobulin loci. However, some features are unique to A. jamaicensis , including an e...

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Literature Corpus work: a98f00bc-7170-570f-b8e2-1cdaf556dcc3
DOI: 10.1101/2025.04.10.648212

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