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Article

Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinoma

2020-05-15

Abstract excerpt

<title>Abstract</title> <p>Background: Overexpression of survivin plays a crucial role in tumorigenesis and correlates with poor prognosis in human malignancies. Thus, survivin has been proposed as an attractive target for new anti-tumor interventions. <h4>Methods:</h4> A natural product library was used for natural compound screening through MTS assay. The expression of survivin in oral squamous cell carcinoma (...

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Literature Corpus work
a9881e37-6529-5e79-979a-e5ce0fb6d776
DOI
10.21203/rs.3.rs-20813/v2
Open publication

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Promotion of ubiquitination-dependent survivin destruction contributes to xanthohumol-mediated tumor suppression and overcomes radioresistance in human oral squamous cell carcinomaDOI 10.21203/rs.3.rs-20813/v2
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