Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recent Advances on Small-Molecule Survivin Inhibitors

16 Jan 2015

Abstract excerpt

Survivin, a member of the inhibitor of apoptosisproteins family, is highly expressed in most human neoplasms, but its expression is very low or undetectable in terminally differentiated normal tissues. Survivin has been shown to inhibit cancer cell apoptosis and promote cell proliferation. The overexpression of survivin closely correlates with tumor progression and drug resistance. Because of its key role in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Cell death mechanisms and regulation
Share to Computational Drug Discovery Methods

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25613234
DOI: 10.2174/0929867322666150114102146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 10 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recent Advances on Small-Molecule Survivin InhibitorsPMID 25613234Read ↗

Survivin Small Molecules Inhibitors: Recent Advances and ChallengesSemantic proximity Read ↗

Investigations of survivin: the past, present and futureSemantic proximity Read ↗

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic StrategiesSemantic proximity Read ↗

Clinical aspects for survivin: a crucial molecule for targeting drug-resistant cancersSemantic proximity Read ↗

The role of survivin as a new target of diagnosis and treatment in human cancer.Semantic proximity Read ↗

Emerging Importance of Survivin in Stem Cells and Cancer: the Development of New Cancer TherapeuticsSemantic proximity Read ↗

Survivin as a Therapeutic Target for the Treatment of Human CancerSemantic proximity Read ↗

Survivin study: an update of "what is the next wave"?Semantic proximity Read ↗

Blocking survivin to kill cancer cells.Semantic proximity Read ↗

Cancer cells survive with survivinSemantic proximity Read ↗

Survivin: A molecular biomarker in cancer.Semantic proximity Read ↗

Survivin study: What is the next wave?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.