Article

TMCC2 Associates with Alzheimer’s Disease Pathology in the Human Brain

2021-08-16

Abstract excerpt

Transmembrane and Coiled-Coil 2 (TMCC2) is a protein that forms complexes with both apolipoprotein E (apoE) and the amyloid protein precursor (APP), two proteins central to the etiology of Alzheimer’s disease (AD). Here we have carried out the first investigation of TMCC2 expression in the human brain, where TMCC2 immunoreactivity is primarily neuronal. We also examined TMCC2 localization in late onset AD brains,e...

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Literature Corpus work: a964e845-bf0e-540a-8789-693dbe6a14c1
DOI: 10.1101/2021.08.14.456332

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