Article

Human cerebral organoids capture the spatiotemporal complexity and disease dynamics of UBE3A

2019-08-22

Abstract excerpt

<h4>SUMMARY</h4> Human neurodevelopment and its associated diseases are complex and challenging to study. This has driven recent excitement for human cerebral organoids (hCOs) as research and screening tools. These models are steadily proving their utility; however, it remains unclear what limits they will face in recapitulating the complexities of neurodevelopment and disease. Here we show that their utility ext...

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Literature Corpus work: a92836bd-665d-5fcc-9228-4ad34a624703
DOI: 10.1101/742213

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