Article
Neurodevelopmental disorders-high-resolution rethinking of disease modeling.
Molecular psychiatry - 1 Jan 2023
Khodosevich Konstantin, Sellgren Carl M
Abstract excerpt
Neurodevelopmental disorders arise due to various risk factors that can perturb different stages of brain development, and a combinatorial impact of these risk factors programs the phenotype in adulthood. While modeling the complete phenotype of a neurodevelopmental disorder is challenging, individual developmental perturbations can be successfully modeled in vivo in animals and in vitro in human cellular models....
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