Article

Spatial and single-cell transcriptomics illuminate bat immunity and barrier tissue evolution

2023-11-02

Abstract excerpt

The Egyptian fruit bat displays tolerance to lethal viruses and unique dietary adaptations, but the molecular basis for this is poorly understood. To this end, we generated detailed maps of bat gut, lung and blood cells using spatial and single-cell transcriptomics. We compared bat with mouse and human cells to reveal divergence in genetic programs associated with environmental interactions and immune responses. C...

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Literature Corpus work: a90b153c-0b51-52f1-bd5e-f6f8dbcd8f1d
DOI: 10.1101/2023.10.30.564705

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