Article

Large-scale computational analyses of gut microbial CAZyme repertoires enabled by Cayman

2024-01-08

Abstract excerpt

Carbohydrate-active enzymes (CAZymes) are crucial for digesting glycans, but bioinformatics tools for CAZyme profiling and interpretation of substrate preferences in microbial community data are lacking. To address this, we developed a CAZyme profiler (Cayman) and a hierarchical substrate annotation scheme. Leveraging these, we genomically survey CAZymes in human gut microbes (n=107,683 genomes), which suggests no...

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Literature Corpus work: 0c0eb8fa-90b4-5ece-97e7-6fed9bd445ab
DOI: 10.1101/2024.01.08.574624

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