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Protease activities of vaginal <i>Porphyromonas</i> species disrupt coagulation and extracellular matrix in the cervicovaginal niche

2021-07-07

Abstract excerpt

Porphyromonas asaccahrolytica and Porphyromonas uenonis are frequently isolated from the human vagina and are linked to bacterial vaginosis and preterm labour. However, little is known about the pathogenesis mechanisms of these bacteria. The related oral opportunistic pathogen, Porphyromonas gingivalis, is comparatively well-studied and known to secrete numerous extracellular matrix-targeting proteases. Among th...

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Literature Corpus work
f0375729-ae48-5b66-a9a2-130fdee956c8
DOI
10.1101/2021.07.07.447795
Open publication

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