Article

Copy-number alterations reshape the classification of diffuse intrinsic pontine gliomas. First exome sequencing results of the BIOMEDE trial

2021-04-30

Abstract excerpt

Diffuse intrinsic pontine gliomas (DIPG) is an incurable neoplasm occurring mainly in children for which no progress was made in the last decades. The randomized phase II BIOMEDE trial compared three drugs (everolimus, dasatinib, erlotinib) combined with irradiation. The present report describes whole exome sequencing (WES) results for the first 100 patients randomized. Copy-number-Alteration (CNA) unsupervised cl...

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Literature Corpus work: a8dfadeb-1bb8-575f-8c21-68460805800b
DOI: 10.1101/2021.04.29.21256183

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