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Article

Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma.

Pediatric blood & cancer - 1 Apr 2012

Grill Jacques, Puget Stephanie, Andreiuolo Felipe, Philippe Cathy, MacConaill Laura, Kieran Mark W

Abstract excerpt

Diffuse intrinsic pontine gliomas (DIPG) can not be cured with current treatment modalities. Targeted therapy in this disease would benefit from advanced technologies detecting relevant drugable mutations. Twenty patients with classic newly diagnosed DIPG underwent stereotactic biopsies and were analyzed for the presence of 983 different mutations in 115 oncogenes and tumor-suppressor genes using OncoMap, a mass...

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Source

Identifiers

PMID: 22190243
DOI: 10.1002/pbc.24060

Genes

ATM
MPL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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