Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The integrated genomic and epigenomic landscape of brainstem glioma

17 Jun 2020

Abstract excerpt

Brainstem gliomas are a heterogeneous group of tumors that encompass both benign tumors cured with surgical resection and highly lethal cancers with no efficacious therapies. We perform a comprehensive study incorporating epigenetic and genomic analyses on a large cohort of brainstem gliomas, including Diffuse Intrinsic Pontine Gliomas. Here we report, from DNA methylation data, distinct clusters termed H3-Pons,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Epigenetics and DNA Methylation
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32555164
DOI: 10.1038/s41467-020-16682-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The integrated genomic and epigenomic landscape of brainstem gliomaPMID 32555164Read ↗

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.Semantic proximity Read ↗

The Molecular, Neurological, and Clinical Features of Diffuse Intrinsic Pontine GliomaSemantic proximity Read ↗

Pathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine GliomaSemantic proximity Read ↗

Epigenetic Targeted Therapy for Diffuse Intrinsic Pontine GliomaSemantic proximity Read ↗

Epigenetic reprogramming and chromatin accessibility in pediatric diffuse intrinsic pontine gliomas: a neural developmental disease.Semantic proximity Read ↗

Clinicopathology of diffuse intrinsic pontine glioma and its redefined genomic and epigenomic landscape.Semantic proximity Read ↗

Diffuse Intrinsic Pontine Glioma: New Pathophysiological Insights and Emerging Therapeutic Targets.Semantic proximity Read ↗

Diffuse intrinsic pontine glioma: current insights and future directionsSemantic proximity Read ↗

Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG.Semantic proximity Read ↗

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade gliomaSemantic proximity Read ↗

Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomasSemantic proximity Read ↗

Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.